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Oct 23

AminoActive – Natural Pain Relief

The Science Behind AminioActiv

The following data was obtained from 5 years of studies and trials performed on AminoActiv and have been validated as displaying the effectiveness of AminoActiv along with a subjective measure of how it compares to other non-prescription musculoskeletal pain relievers.

Inflammation:

It is well known that previous scientific literature has shown and documented the natural occurring compound from which AminoActiv is derived has chemical attributes that render them as supporting natural anti-inflammatory activity.

To demonstrate this, when cultured cells are treated with bacterial toxins, they produce and release prostaglandins, similar to injured tissue or inflammatory responses. The data below shows that AminoActiv effectively supports the reduced release of prostaglandins (PGE), a major cause of the routine pain response that occurs as a result of inflammation of over-worked muscles and joints. The data shows that this activity is dependent upon the dose of AminoActiv with higher concentrations producing the greatest amount of support of prostaglandin release inhibition.


Several non-prescription drugs currently on the market are specifically designed as anti-inflammatory agents that inhibit the cyclooxygenase pathway (COX-2), which is the major cause for the production of prostaglandins following inflammation or tissue injury. Long-term inhibition of this pathway is also the major cause of the negative side effects of COX-2 Inhibitors like ibuprofen, naproxen, aspirin, etc. It was shown that AminoActiv does not inhibit the COX-2 enzyme, but instead reduces prostaglandin release from cells by a different mechanism.

AminoActiv seems to support and promote greater stability of the mitochondrial membrane, leading to improved mitochondrial function and less membrane damage that initiates prostaglandin synthesis and thus, less inflammation. This means that AminoActiv does not have the negative side effects associated with non-steroidal anti-inflammatory drugs (NSAID) that are COX-2 inhibitors.

These side effects include contraindications with the stomach, kidneys, and liver. The healthy support of the body’s anti-inflammation by AminoActiv is a very effective when compared to one of the top NSAIDs currently on the market, as shown below.

The data show that AminoActiv was as equally effective as the leading NSAID, ibuprofen, in supporting the reduction or slowing of the production and release of prostaglandin from cells treated with the bacterial toxin LPS (lipopolysaccharide).

LACTIC ACID EFFECTS

The effect of AminoActiv on the intracellular lactic acid concentration in muscle cells during normal and hypoxic growth conditions is shown in figure 2. Also shown in figure 2 is the comparison of the effect of AminoActiv to SAC (standard amino compounds) in supporting the reduction of lactic acid accumulation. The third chart examines the effects of AminoActiv treatment on supporting a healthy reduction in lactic acid release from skeletal muscle cells during hypoxia (anaerobic activity resulting in insufficient oxygen supply).

The data show that the lactic acid concentrations in both normal and hypoxic cells is decreased following treatment with either SAC or AminoActiv, however AminoActiv consistently reduced the intracellular accumulation of lactate more than SAC.

Figure 3 represents the data generated from experiments that examine the effect of both AminoActiv treatment and SAC on the release of lactic acid from cultured cells. Similar to the effect observed with the treatments on accumulation of lactate in the cellular compartments, both AminoActiv and SAC decreased the release of lactic acid from cells during hypoxic conditions. AminoActiv treatment showed a significant reduction in the release of lactic acid when compared to the control SAC. This significant reduction in lactic acid release was even more evident at four hours of hypoxic growth conditions.

In summary, the research from data compiled above clearly showed first that lactic acid is constantly being produced in the cell at some level and in much greater amounts during hypoxic conditions. The data also illustrates that AminoActiv is significantly more effective than SAC in the reduction of lactic acid accumulation and release from cells.

Since less lactic acid is generated and released with AminoActiv treatment, it is proposed that the pain and soreness associated with lactate accumulation in muscle and other tissues is greatly reduced. Again, no other product on the market targets this source of routine pain.

For more information please click here: All Natural Pain Relief

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